Pseudomonas aeruginosa PAO1, PA0099

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0099
Name
Replicon chromosome
Genomic location 120164 - 121324 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
CommentHcp Secretion Island-I-encoded type VI secretion system (H1-T6SS)

Cross-References

RefSeq NP_248789.1
GI 15595297
Affymetrix PA0099_at
Entrez 880737
GenBank AAG03489.1
INSDC AAG03489.1
NCBI Locus Tag PA0099
protein_id(GenBank) gb|AAG03489.1|AE004448_8|gnl|PseudoCAP|PA0099
TIGR NTL03PA00100
UniParc UPI00000C4F34
UniProtKB Acc Q9I733
UniProtKB ID Q9I733_PSEAE
UniRef100 UniRef100_Q9I733
UniRef50 UniRef50_Q9I733
UniRef90 UniRef90_Q9I733

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI effector protein
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 33.96
Kyte-Doolittle Hydrophobicity Value -0.618
Molecular Weight (kDa) 41.3
Isoelectric Point (pI) 10.32

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 28 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000097 (328 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0099

Human Homologs

References

The VgrG proteins are "à la carte" delivery systems for bacterial type VI effectors.
Hachani A, Allsopp LP, Oduko Y, Filloux A
J Biol Chem 2014 Jun 20;289(25):17872-84
PubMed ID: 24794869