Pseudomonas aeruginosa PAO1, PA0154 (pcaG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0015976 carbon utilization
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Biological Process GO:0044248 cellular catabolic process
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Molecular Function GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:2.60.130.10
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019439 aromatic compound catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd03463
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005506 iron ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:2.60.130.10
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00083
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006725 cellular aromatic compound metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00083
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008199 ferric iron binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00083
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0018578 protocatechuate 3,4-dioxygenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd03463
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00083
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCyc PROTOCATECHUATE-ORTHO-CLEAVAGE-PWY protocatechuate degradation II (ortho-cleavage pathway) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Aromatic compound catabolism ECO:0000037
not_recorded
MetaCyc 4-sulfocatechol degradation InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae00362 Benzoate degradation 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00624 Polycyclic aromatic hydrocarbon degradation InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00362 Benzoate degradation InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae01220 Degradation of aromatic compounds 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00775 Dioxygenase IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal 41 191 2.2E-12
CDD cd03463 3,4-PCD_alpha IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit 6 200 5.76128E-87
TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit 9 201 2.6E-75
SUPERFAMILY SSF49482 IPR015889 Intradiol ring-cleavage dioxygenase, core 5 201 3.53E-57
Gene3D G3DSA:2.60.130.10 IPR015889 Intradiol ring-cleavage dioxygenase, core 2 201 3.7E-77
ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal 52 80 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.