Pseudomonas aeruginosa PAO1, PA0197 (tonB2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0197
Name
tonB2
Replicon chromosome
Genomic location 227382 - 228194 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_248888.1
GI 15595394
Affymetrix PA0197_at
Entrez 879472
GenBank AAG03586.1
INSDC AAG03586.1
NCBI Locus Tag PA0197
protein_id(GenBank) gb|AAG03586.1|AE004458_1|gnl|PseudoCAP|PA0197
TIGR NTL03PA00198
UniParc UPI00000D4276
UniProtKB Acc Q9RMT3
UniProtKB ID TONB2_PSEAE
UniRef100 UniRef100_Q9RMT3
UniRef50 UniRef50_Q9RMT3
UniRef90 UniRef90_Q9RMT3

Product

Feature Type CDS
Coding Frame 1
Product Name
TonB2
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 9.44
Kyte-Doolittle Hydrophobicity Value -0.412
Molecular Weight (kDa) 28.8
Isoelectric Point (pI) 10.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 132 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000196 (454 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0197
Search term: tonB2
Search term: TonB2

Human Homologs

References

The Pseudomonas aeruginosa tonB gene encodes a novel TonB protein.
Poole K, Zhao Q, Neshat S, Heinrichs DE, Dean CR
Microbiology (Reading) 1996 Jun;142 ( Pt 6):1449-1458
PubMed ID: 8704984
A second tonB gene in Pseudomonas aeruginosa is linked to the exbB and exbD genes.
Zhao Q, Poole K
FEMS Microbiol Lett 2000 Mar 1;184(1):127-32
PubMed ID: 10689178