Pseudomonas aeruginosa PAO1, PA0257

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0257
Name
Replicon chromosome
Genomic location 288384 - 289175 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248948.1
GI 15595454
Affymetrix PA0257_at
Entrez 880116
GenBank AAG03646.1
INSDC AAG03646.1
NCBI Locus Tag PA0257
protein_id(GenBank) gb|AAG03646.1|AE004463_11|gnl|PseudoCAP|PA0257
TIGR NTL03PA00258
UniParc UPI00000C4FC6
UniProtKB Acc Q9I6N2
UniProtKB ID Q9I6N2_PSEAE
UniRef100 UniRef100_Q9I6N2
UniRef50 UniRef50_Q57QF8
UniRef90 UniRef90_Q9I6N2

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Charge (pH 7) 26.74
Kyte-Doolittle Hydrophobicity Value -0.641
Molecular Weight (kDa) 30.6
Isoelectric Point (pI) 10.82

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 365 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000255 (913 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0257

Human Homologs

References

Use of a novel approach, termed island probing, identifies the Shigella flexneri she pathogenicity island which encodes a homolog of the immunoglobulin A protease-like family of proteins.
Rajakumar K, Sasakawa C, Adler B
Infect Immun 1997 Nov;65(11):4606-14
PubMed ID: 9353040
Genomic analysis of a pathogenicity island in uropathogenic Escherichia coli CFT073: distribution of homologous sequences among isolates from patients with pyelonephritis, cystitis, and Catheter-associated bacteriuria and from fecal samples.
Guyer DM, Kao JS, Mobley HL
Infect Immun 1998 Sep;66(9):4411-7
PubMed ID: 9712795