Pseudomonas aeruginosa PAO1, PA0316 (serA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02826
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00389
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCyc SER-GLYSYN-PWY superpathway of L-serine and glycine biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc SERSYN-PWY L-serine biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCAP Glycine, serine and threonine metabolism ECO:0000037
not_recorded
KEGG pae00680 Methane metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.70.260 - - - 328 408 4.2E-33
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 108 295 3.19E-52
Gene3D G3DSA:3.40.50.720 - - - 14 313 4.9E-111
Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 14 326 3.9E-38
CDD cd04901 ACT_3PGDH - - 340 408 3.79223E-27
CDD cd12176 PGDH_3 - - 11 315 0.0
FunFam G3DSA:3.40.50.720:FF:000041 D-3-phosphoglycerate dehydrogenase - - 109 297 8.5E-78
Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain 119 294 8.3E-47
SUPERFAMILY SSF55021 ACT-like IPR045865 ACT-like domain 334 408 2.18E-16
PANTHER PTHR43761 D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630) - - 10 318 2.9E-67
FunFam G3DSA:3.30.70.260:FF:000007 D-3-phosphoglycerate dehydrogenase - - 328 408 1.9E-39
Gene3D G3DSA:3.40.50.720 - - - 109 297 4.9E-111
SUPERFAMILY SSF52283 Formate/glycerate dehydrogenase catalytic domain-like - - 7 136 3.4E-51

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.