Pseudomonas aeruginosa PAO1, PA0357 (mutM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006281 DNA repair
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
12445642 Reviewed by curator
Biological Process GO:0006281 DNA repair
IGI
Inferred from Genetic Interaction
ECO:0000316
genetic interaction evidence used in manual assertion
12445642 Reviewed by curator
Molecular Function GO:0016787 hydrolase activity
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
12445642 Reviewed by curator
Molecular Function GO:0008270 zinc ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS51068
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006284 base-excision repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS51068
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS51068
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS51066
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006289 nucleotide-excision repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01232
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003684 damaged DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS51068
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00577
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS01242
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF46946
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS51068
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae03410 Base excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF06827 Zinc finger found in FPG and IleRS IPR010663 Zinc finger, FPG/IleRS-type 242 269 6.4E-9
ProSiteProfiles PS51066 Zinc finger FPG-type profile. IPR000214 Zinc finger, DNA glycosylase/AP lyase-type 236 270 12.59
Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding 130 219 5.2E-23
SUPERFAMILY SSF81624 IPR035937 MutM-like, N-terminal 2 135 1.15E-40
Gene3D G3DSA:1.10.8.50 132 270 3.6E-42
TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase IPR020629 Formamidopyrimidine-DNA glycosylase 1 269 1.1E-91
CDD cd08966 EcFpg-like_N 2 117 2.90555E-53
Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain 1 115 1.6E-33
SMART SM01232 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding 130 222 6.8E-46
ProSiteProfiles PS51068 Formamidopyrimidine-DNA glycosylase catalytic domain profile. IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain 2 113 37.243
SUPERFAMILY SSF46946 IPR010979 Ribosomal protein S13-like, H2TH 131 222 1.09E-27
Gene3D G3DSA:3.20.190.10 IPR035937 MutM-like, N-terminal 2 129 1.4E-40
Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. IPR020629 Formamidopyrimidine-DNA glycosylase 1 270 44.769
SMART SM00898 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain 2 116 1.5E-55
ProSitePatterns PS01242 Zinc finger FPG-type signature. IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site 245 269 -
SUPERFAMILY SSF57716 218 269 1.17E-16

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.