Pseudomonas aeruginosa PAO1, PA0401

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009117 nucleotide metabolic process
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Molecular Function GO:0046872 metal ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01317
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004151 dihydroorotase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01317
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006221 pyrimidine nucleotide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01317
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF51338
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016787 hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01979
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR43668 ALLANTOINASE - - 1 420 8.6E-80
NCBIfam TIGR00857 JCVI: dihydroorotase, multifunctional complex type - - 21 421 2.3E-87
Pfam PF01979 Amidohydrolase family IPR006680 Amidohydrolase-related 203 419 3.3E-13
Gene3D G3DSA:3.20.20.140 - - - 57 368 5.9E-108
CDD cd01317 DHOase_IIa IPR004722 Dihydroorotase 45 413 0.0
SUPERFAMILY SSF51556 Metallo-dependent hydrolases IPR032466 Metal-dependent hydrolase 56 367 4.4E-88
SUPERFAMILY SSF51338 Composite domain of metallo-dependent hydrolases IPR011059 Metal-dependent hydrolase, composite domain superfamily 1 422 4.32E-24
Gene3D G3DSA:2.30.40.10 Urease, subunit C, domain 1 IPR011059 Metal-dependent hydrolase, composite domain superfamily 20 419 5.9E-108

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.