Pseudomonas aeruginosa PAO1, PA0407 (gshB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006750 glutathione biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01380
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.30.1490.20
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004363 glutathione synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01380
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class
Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00270 Cysteine and methionine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Glutathione metabolism ECO:0000037
not_recorded
PseudoCAP Glutamate metabolism ECO:0000037
not_recorded
PseudoCyc GLUTATHIONESYN-PWY glutathione biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00480 Glutathione metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain IPR004215 Prokaryotic glutathione synthetase, N-terminal 4 121 2.1E-44
SUPERFAMILY SSF56059 Glutathione synthetase ATP-binding domain-like - - 124 311 2.83E-57
Hamap MF_00162 Glutathione synthetase [gshB]. IPR006284 Glutathione synthetase, prokaryotic 1 317 173.70871
Gene3D G3DSA:3.40.50.20 - - - 8 302 3.3E-128
NCBIfam TIGR01380 JCVI: glutathione synthase IPR006284 Glutathione synthetase, prokaryotic 4 313 0.0
PANTHER PTHR21621 RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN - - 1 314 1.0E-56
Gene3D G3DSA:3.30.470.20 - - - 116 301 3.3E-128
SUPERFAMILY SSF52440 PreATP-grasp domain IPR016185 Pre-ATP-grasp domain superfamily 3 123 1.29E-42
FunFam G3DSA:3.40.50.20:FF:000009 Glutathione synthetase - - 8 116 4.0E-47
Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain IPR004218 Prokaryotic glutathione synthetase, ATP-binding 125 297 5.0E-80
FunFam G3DSA:3.30.470.20:FF:000010 Glutathione synthetase - - 188 301 1.1E-52
Gene3D G3DSA:3.30.1490.20 - IPR013815 ATP-grasp fold, subdomain 1 138 202 3.3E-128
FunFam G3DSA:3.30.1490.20:FF:000009 Glutathione synthetase - - 138 202 2.0E-32

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.