Pseudomonas aeruginosa PAO1, PA0413 (chpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF47226
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01584
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006935 chemotaxis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01584
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Motility & Attachment Other PAO1 genes in this class
Two-component regulatory systems Other PAO1 genes in this class
Chemotaxis Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Chemotaxis ECO:0000037
not_recorded
PseudoCAP Pilin biosynthesis ECO:0000037
not_recorded
PseudoCAP Two-component System ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
ProSiteProfiles PS50110 Response regulatory domain profile. IPR001789 Signal transduction response regulator, receiver domain 2352 2468 43.179
ProSiteProfiles PS50894 Histidine-containing phosphotransfer (HPt) domain profile. IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 860 967 15.843
SMART SM00073 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1522 1619 0.0095
CDD cd16916 HATPase_CheA-like 1998 2173 9.80694E-84
Gene3D G3DSA:3.30.565.10 IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1989 2175 7.4E-53
SMART SM00260 IPR002545 CheW-like domain 2168 2318 2.0E-34
CDD cd00156 REC IPR001789 Signal transduction response regulator, receiver domain 2354 2467 1.65788E-33
Gene3D G3DSA:1.20.120.160 IPR036641 HPT domain superfamily 1358 1487 1.1E-25
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 864 960 3.35034E-10
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 10 98 2.8E-8
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1364 1457 6.3E-14
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 1522 1644 1.83E-26
Gene3D G3DSA:2.40.50.180 2199 2273 1.1E-34
ProSiteProfiles PS50894 Histidine-containing phosphotransfer (HPt) domain profile. IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1665 1769 19.718
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 7 130 1.83E-23
SUPERFAMILY SSF52172 IPR011006 CheY-like superfamily 2350 2469 3.98E-36
SMART SM00448 IPR001789 Signal transduction response regulator, receiver domain 2351 2464 2.9E-37
MobiDBLite mobidb-lite consensus disorder prediction 658 679 -
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 2039 2175 5.5E-16
Pfam PF01584 CheW-like domain IPR002545 CheW-like domain 2181 2320 9.0E-23
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2160 2173 1.5E-10
ProSiteProfiles PS50109 Histidine kinase domain profile. IPR005467 Histidine kinase domain 1943 2176 21.856
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1670 1774 4.52315E-13
Gene3D G3DSA:1.20.120.160 IPR036641 HPT domain superfamily 1183 1285 1.9E-7
Coils Coil 1370 1390 -
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 1041 1164 4.84E-19
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1041 1132 1.70437E-5
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1524 1623 4.4E-14
ProSiteProfiles PS50851 CheW-like domain profile. IPR002545 CheW-like domain 2178 2323 18.831
Gene3D G3DSA:1.20.120.160 IPR036641 HPT domain superfamily 1019 1133 2.6E-16
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 864 989 4.6E-27
MobiDBLite mobidb-lite consensus disorder prediction 565 618 -
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1522 1620 4.7859E-15
SMART SM00073 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1362 1459 6.6E-7
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 1670 1778 4.19E-20
Gene3D G3DSA:2.30.30.40 2176 2313 1.1E-34
Gene3D G3DSA:1.20.120.160 IPR036641 HPT domain superfamily 863 997 5.6E-26
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2136 2154 1.5E-10
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1362 1460 2.82873E-15
SMART SM01231 IPR004105 Histidine kinase CheA-like, homodimeric domain 1851 1990 1.3E-11
Gene3D G3DSA:1.20.120.160 IPR036641 HPT domain superfamily 1514 1649 9.3E-25
SMART SM00073 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 864 961 3.8E-6
ProSiteProfiles PS50894 Histidine-containing phosphotransfer (HPt) domain profile. IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1358 1462 19.479
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 2353 2465 1.4E-27
SMART SM00073 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1041 1144 0.49
Coils Coil 1889 1909 -
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1043 1129 2.4E-11
ProSiteProfiles PS50894 Histidine-containing phosphotransfer (HPt) domain profile. IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1522 1622 18.364
ProSiteProfiles PS50894 Histidine-containing phosphotransfer (HPt) domain profile. IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1037 1143 17.249
SMART SM00387 IPR003594 Histidine kinase/HSP90-like ATPase 2035 2176 1.3E-22
MobiDBLite mobidb-lite consensus disorder prediction 987 1035 -
SUPERFAMILY SSF55874 IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1992 2173 7.99E-36
Coils Coil 1752 1779 -
Gene3D G3DSA:3.40.50.12740 2351 2472 1.1E-38
Gene3D G3DSA:1.20.120.160 IPR036641 HPT domain superfamily 14 127 2.8E-6
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 1362 1484 1.83E-27
Gene3D G3DSA:1.20.120.160 IPR036641 HPT domain superfamily 1669 1798 1.1E-20
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1671 1764 3.7E-15
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 433 556 1.94E-14
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 1184 1304 1.91E-15
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2080 2094 1.5E-10
SUPERFAMILY SSF50341 IPR036061 CheW-like domain superfamily 2175 2314 1.7E-21
Coils Coil 232 252 -
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 866 953 1.5E-13
SMART SM00073 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1669 1766 6.4E-4

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.