Pseudomonas aeruginosa PAO1, PA0426 (mexB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Operons

Operon name: mexAB-oprM (3 gene members)
Locus Tag Gene Name Description Start End Strand Type
PA0425 mexA Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexA precursor 472024 473175 + CDS
Gene Details
PA0426 mexB Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter MexB 473191 476331 + CDS
Gene Details
PA0427 oprM Major intrinsic multiple antibiotic resistance efflux outer membrane protein OprM precursor 476333 477790 + CDS
Gene Details
Evidence
A transcription unit is inferred from author statement. In this case, there is often a set of adjacent genes, encoded in the same direction, coding for products that participate in the same metabolic pathway or biological process.
References
MexR repressor of the mexAB-oprM multidrug efflux operon of Pseudomonas aeruginosa: identification of MexR binding sites in the mexA-mexR intergenic region.
Evans K, Adewoye L, Poole K
J. Bacteriol. 2001 Feb;183(3):807-12
PubMed ID: 11208776
Cross-References
PseudoCAP: 41729
Operon name: mexAB-oprM (3 gene members)
Locus Tag Gene Name Description Start End Strand Type
PA0425 mexA Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexA precursor 472024 473175 + CDS
Gene Details
PA0426 mexB Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter MexB 473191 476331 + CDS
Gene Details
PA0427 oprM Major intrinsic multiple antibiotic resistance efflux outer membrane protein OprM precursor 476333 477790 + CDS
Gene Details
Evidence
A transcription unit is inferred from author statement. In this case, there is often a set of adjacent genes, encoded in the same direction, coding for products that participate in the same metabolic pathway or biological process.
References
MexR repressor of the mexAB-oprM multidrug efflux operon of Pseudomonas aeruginosa: identification of MexR binding sites in the mexA-mexR intergenic region.
Evans K, Adewoye L, Poole K
J. Bacteriol. 2001 Feb;183(3):807-12
PubMed ID: 11208776
Cross-References
PseudoCAP: 41728
Operon name: mexAB-oprM (3 gene members)
Locus Tag Gene Name Description Start End Strand Type
PA0425 mexA Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexA precursor 472024 473175 + CDS
Gene Details
PA0426 mexB Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter MexB 473191 476331 + CDS
Gene Details
PA0427 oprM Major intrinsic multiple antibiotic resistance efflux outer membrane protein OprM precursor 476333 477790 + CDS
Gene Details
Evidence
A transcription unit is inferred from author statement. In this case, there is often a set of adjacent genes, encoded in the same direction, coding for products that participate in the same metabolic pathway or biological process.
References
nalD encodes a second repressor of the mexAB-oprM multidrug efflux operon of Pseudomonas aeruginosa.
Morita Y, Cao L, Gould VC, Avison MB, Poole K
J. Bacteriol. 2006 Dec;188(24):8649-54
PubMed ID: 17028276
Cross-References
PseudoCAP: 41727
Operon name: mexAB-oprM (3 gene members)
Locus Tag Gene Name Description Start End Strand Type
PA0425 mexA Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexA precursor 472024 473175 + CDS
Gene Details
PA0426 mexB Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter MexB 473191 476331 + CDS
Gene Details
PA0427 oprM Major intrinsic multiple antibiotic resistance efflux outer membrane protein OprM precursor 476333 477790 + CDS
Gene Details
Evidence
A transcription unit is inferred from author statement. In this case, there is often a set of adjacent genes, encoded in the same direction, coding for products that participate in the same metabolic pathway or biological process.
References
MexR repressor of the mexAB-oprM multidrug efflux operon of Pseudomonas aeruginosa: identification of MexR binding sites in the mexA-mexR intergenic region.
Evans K, Adewoye L, Poole K
J. Bacteriol. 2001 Feb;183(3):807-12
PubMed ID: 11208776
Cross-References
PseudoCAP: 41772
Operon name: mexA-mexB-oprM (3 gene members)
Locus Tag Gene Name Description Start End Strand Type
PA0425 mexA Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexA precursor 472024 473175 + CDS
Gene Details
PA0426 mexB Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter MexB 473191 476331 + CDS
Gene Details
PA0427 oprM Major intrinsic multiple antibiotic resistance efflux outer membrane protein OprM precursor 476333 477790 + CDS
Gene Details
Evidence
Computationally-predicted.
References
DOOR: a database for prokaryotic operons.
Mao F, Dam P, Chou J, Olman V, Xu Y
Nucleic Acids Res. 2009 Jan;37(Database issue):D459-63
PubMed ID: 18988623
Cross-References
DOOR: 13192