Pseudomonas aeruginosa PAO1, PA0427 (oprM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0042910 xenobiotic transmembrane transporter activity
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
8540696 Reviewed by curator
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01845
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055085 transmembrane transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02321
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0015562 efflux transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02321
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0022857 transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01845
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Membrane proteins Other PAO1 genes in this class
Antibiotic resistance and susceptibility Other PAO1 genes in this class
Transport of small molecules Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01501 beta-Lactam resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae02024 Quorum sensing 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Coils Coil Coil - - 223 243 -
Pfam PF02321 Outer membrane efflux protein IPR003423 Outer membrane efflux protein 284 464 4.5E-27
Pfam PF02321 Outer membrane efflux protein IPR003423 Outer membrane efflux protein 66 256 8.4E-28
Gene3D G3DSA:1.20.1600.10 Outer membrane efflux proteins (OEP) - - 57 466 0.0
NCBIfam TIGR01845 JCVI: efflux transporter outer membrane subunit IPR010131 RND efflux system, outer membrane lipoprotein, NodT 9 466 0.0
SUPERFAMILY SSF56954 Outer membrane efflux proteins (OEP) - - 1 468 1.26E-120
PANTHER PTHR30203 OUTER MEMBRANE CATION EFFLUX PROTEIN - - 4 478 9.0E-112
Gene3D G3DSA:2.20.200.10 Outer membrane efflux proteins (OEP) - - 103 355 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.