Pseudomonas aeruginosa PAO1, PA0432 (sahH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00563
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004013 adenosylhomocysteinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00739
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019510 S-adenosylhomocysteine catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00563
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
UniPathway UPA00314 L-homocysteine biosynthesis InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00270 Cysteine and methionine metabolism InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae00270 Cysteine and methionine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 199 381 1.47E-50
Gene3D G3DSA:3.40.50.1480 380 469 4.3E-33
Pfam PF05221 S-adenosyl-L-homocysteine hydrolase IPR000043 Adenosylhomocysteinase-like 12 149 1.9E-70
Hamap MF_00563 Adenosylhomocysteinase [ahcY]. IPR034373 Adenosylhomocysteinase 8 461 43.835
ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site 221 237 -
PIRSF PIRSF001109 IPR000043 Adenosylhomocysteinase-like 2 469 4.9E-184
TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase IPR000043 Adenosylhomocysteinase-like 13 461 2.8E-153
Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 199 381 1.5E-56
CDD cd00401 SAHH IPR000043 Adenosylhomocysteinase-like 22 456 0.0
Gene3D G3DSA:3.40.50.720 206 379 2.2E-71
ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site 84 98 -
SUPERFAMILY SSF52283 10 198 8.5E-108
Gene3D G3DSA:3.40.50.1480 10 205 2.9E-91
SMART SM00996 IPR000043 Adenosylhomocysteinase-like 12 468 1.0E-276
SMART SM00997 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 199 381 4.8E-82
SUPERFAMILY SSF52283 382 469 8.5E-108

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.