Pseudomonas aeruginosa PAO1, PA0504 (bioD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004141 dethiobiotin synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006755
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009102 biotin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006755
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000287 magnesium ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006755
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006755
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Biotin metabolism ECO:0000037
not_recorded
PseudoCyc BIOTIN-SYNTHESIS-II-PWY biotin biosynthesis II 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
KEGG pae00780 Biotin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF13500 AAA domain - - 4 212 1.3E-35
PANTHER PTHR43210 DETHIOBIOTIN SYNTHETASE IPR004472 Dethiobiotin synthase BioD 1 217 1.8E-59
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 1 214 6.02E-60
PIRSF PIRSF006755 DTB_synth IPR004472 Dethiobiotin synthase BioD 1 226 1.9E-76
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 3 222 2.1E-68
Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. IPR004472 Dethiobiotin synthase BioD 1 218 28.999653
FunFam G3DSA:3.40.50.300:FF:000292 ATP-dependent dethiobiotin synthetase BioD - - 2 224 5.5E-80
CDD cd03109 DTBS - - 2 194 2.57187E-47
NCBIfam TIGR00347 JCVI: dethiobiotin synthase IPR004472 Dethiobiotin synthase BioD 5 176 6.2E-44

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.