Pseudomonas aeruginosa PAO1, PA0548 (tktA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.920
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004802 transketolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00232
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Energy metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00030 Pentose phosphate pathway 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Carbon fixation ECO:0000037
not_recorded
PseudoCAP Pentose phosphate cycle ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF52518 IPR029061 Thiamin diphosphate-binding fold 347 526 1.01E-67
CDD cd02012 TPP_TK IPR005474 Transketolase, N-terminal 9 273 1.28011E-144
CDD cd07033 TPP_PYR_DXS_TK_like 358 520 8.7467E-57
TIGRFAM TIGR00232 tktlase_bact: transketolase IPR005478 Transketolase, bacterial-like 6 663 0.0
Gene3D G3DSA:3.40.50.970 326 537 3.5E-83
Pfam PF02779 Transketolase, pyrimidine binding domain IPR005475 Transketolase-like, pyrimidine-binding domain 353 525 8.5E-46
ProSitePatterns PS00802 Transketolase signature 2. IPR020826 Transketolase binding site 467 483 -
ProSitePatterns PS00801 Transketolase signature 1. IPR005474 Transketolase, N-terminal 12 32 -
Gene3D G3DSA:3.40.50.920 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II 538 665 5.4E-42
SMART SM00861 IPR005475 Transketolase-like, pyrimidine-binding domain 354 525 1.3E-69
SUPERFAMILY SSF52922 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II 533 664 1.83E-42
Pfam PF00456 Transketolase, thiamine diphosphate binding domain IPR005474 Transketolase, N-terminal 5 333 0.0
Gene3D G3DSA:3.40.50.970 3 325 0.0
Pfam PF02780 Transketolase, C-terminal domain IPR033248 Transketolase, C-terminal domain 540 655 8.4E-16
SUPERFAMILY SSF52518 IPR029061 Thiamin diphosphate-binding fold 5 320 7.23E-122

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.