Pseudomonas aeruginosa PAO1, PA0576 (rpoD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006355 regulation of transcription, DNA-templated
IDA
Inferred from Direct Assay
ECO:0000002
direct assay evidence
Molecular Function GO:0016987 sigma factor activity
ISS
Inferred from Sequence or Structural Similarity
ECO:0000250
sequence similarity evidence used in manual assertion
1902749 Reviewed by curator
Molecular Function GO:0016987 sigma factor activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.220.120
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02937
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003700 DNA-binding transcription factor activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02937
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006352 DNA-templated transcription, initiation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02937
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00140
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:1.10.601.10 RNA Polymerase Primary Sigma Factor - - 113 452 0.0
Pfam PF04542 Sigma-70 region 2 IPR007627 RNA polymerase sigma-70 region 2 383 452 1.5E-21
Gene3D G3DSA:1.10.10.10 - IPR036388 Winged helix-like DNA-binding domain superfamily 533 617 1.2E-36
Pfam PF04546 Sigma-70, non-essential region IPR007631 RNA polymerase sigma factor 70, non-essential domain 139 352 4.9E-65
Pfam PF04545 Sigma-70, region 4 IPR007630 RNA polymerase sigma-70 region 4 551 604 8.0E-19
SUPERFAMILY SSF88946 Sigma2 domain of RNA polymerase sigma factors IPR013325 RNA polymerase sigma factor, region 2 115 450 7.72E-105
PRINTS PR00046 Major sigma-70 factor signature IPR000943 RNA polymerase sigma-70 431 439 6.5E-31
FunFam G3DSA:1.10.220.120:FF:000001 RNA polymerase sigma factor RpoD - - 4 66 5.2E-32
NCBIfam TIGR02937 JCVI: sigma-70 family RNA polymerase sigma factor IPR014284 RNA polymerase sigma-70 like domain 379 604 3.9E-37
PANTHER PTHR30603 RNA POLYMERASE SIGMA FACTOR RPO - - 11 615 0.0
Pfam PF04539 Sigma-70 region 3 IPR007624 RNA polymerase sigma-70 region 3 462 538 2.2E-30
Coils Coil Coil - - 334 382 -
FunFam G3DSA:1.10.10.10:FF:000004 RNA polymerase sigma factor SigA - - 533 616 9.3E-41
Gene3D G3DSA:1.10.220.120 - IPR042189 Sigma-70 factor, region 1.1 superfamily 4 66 3.4E-29
MobiDBLite mobidb-lite consensus disorder prediction - - 170 220 -
PRINTS PR00046 Major sigma-70 factor signature IPR000943 RNA polymerase sigma-70 591 602 6.5E-31
Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. IPR028630 RNA polymerase sigma factor RpoD 6 616 46.887291
FunFam G3DSA:1.10.10.10:FF:000002 RNA polymerase sigma factor SigA - - 456 532 1.2E-43
Coils Coil Coil - - 577 597 -
SUPERFAMILY SSF88659 Sigma3 and sigma4 domains of RNA polymerase sigma factors IPR013324 RNA polymerase sigma factor, region 3/4-like 513 615 9.16E-27
Pfam PF03979 Sigma-70 factor, region 1.1 IPR007127 RNA polymerase sigma factor 70, region 1.1 6 83 8.6E-30
Pfam PF00140 Sigma-70 factor, region 1.2 IPR009042 RNA polymerase sigma-70 region 1.2 98 128 7.4E-13
Gene3D G3DSA:1.10.10.10 - IPR036388 Winged helix-like DNA-binding domain superfamily 456 532 1.1E-37
MobiDBLite mobidb-lite consensus disorder prediction - - 193 216 -
NCBIfam TIGR02393 JCVI: RNA polymerase sigma factor RpoD IPR012760 RNA polymerase sigma factor RpoD, C-terminal 379 615 9.5E-122
PRINTS PR00046 Major sigma-70 factor signature IPR000943 RNA polymerase sigma-70 555 567 6.5E-31
PRINTS PR00046 Major sigma-70 factor signature IPR000943 RNA polymerase sigma-70 407 420 6.5E-31
CDD cd06171 Sigma70_r4 - - 545 603 6.81896E-12
SUPERFAMILY SSF88659 Sigma3 and sigma4 domains of RNA polymerase sigma factors IPR013324 RNA polymerase sigma factor, region 3/4-like 456 529 1.0E-20
FunFam G3DSA:1.10.601.10:FF:000002 RNA polymerase sigma factor RpoD - - 113 452 0.0
PRINTS PR00046 Major sigma-70 factor signature IPR000943 RNA polymerase sigma-70 576 591 6.5E-31

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.