Pseudomonas aeruginosa PAO1, PA0649 (trpG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0000162 tryptophan biosynthetic process
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
2153661 Reviewed by curator
Molecular Function GO:0004049 anthranilate synthase activity
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
2153661 Reviewed by curator

Functional Classifications Manually Assigned by PseudoCAP

Energy metabolism Other PAO1 genes in this class
Amino acid biosynthesis and metabolism Other PAO1 genes in this class
Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00400 Phenylalanine, tyrosine and tryptophan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Folate biosynthesis ECO:0000037
not_recorded
KEGG pae01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Ubiquinone biosynthesis ECO:0000037
not_recorded
KEGG pae02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-6660 2-heptyl-3-hydroxy-4(1H)-quinolone biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
KEGG pae02024 Quorum sensing 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-6661 4-hydroxy-2(1H)-quinolone biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Phenylalanine, tyrosine and tryptophan biosynthesis ECO:0000037
not_recorded
PseudoCyc COMPLETE-ARO-PWY superpathway of aromatic amino acid biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc ALL-CHORISMATE-PWY superpathway of chorismate metabolism 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
PseudoCyc TRPSYN-PWY L-tryptophan biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 1.4E-13
PRINTS PR00097 Anthranilate synthase component II signature 99 107 2.3E-37
PRINTS PR00097 Anthranilate synthase component II signature 74 85 2.3E-37
PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 1.0E-5
PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.3E-37
SUPERFAMILY SSF52317 IPR029062 Class I glutamine amidotransferase-like 1 192 1.34E-54
PRINTS PR00097 Anthranilate synthase component II signature 119 131 2.3E-37
PRINTS PR00097 Anthranilate synthase component II signature 47 56 2.3E-37
ProSiteProfiles PS51273 Glutamine amidotransferase type 1 domain profile. IPR017926 Glutamine amidotransferase 1 199 30.831
PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 1.0E-5
PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.4E-13
PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.4E-13
Gene3D G3DSA:3.40.50.880 IPR029062 Class I glutamine amidotransferase-like 1 193 3.3E-63
TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain 1 191 2.1E-87
Pfam PF00117 Glutamine amidotransferase class-I IPR017926 Glutamine amidotransferase 4 191 1.6E-55
CDD cd01743 GATase1_Anthranilate_Synthase 2 190 1.31256E-112
PRINTS PR00097 Anthranilate synthase component II signature 169 182 2.3E-37

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.