Pseudomonas aeruginosa PAO1, PA0650 (trpD)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0004048	anthranilate phosphoribosyltransferase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR43285	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016757	transferase activity, transferring glycosyl groups	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00591	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0000162	tryptophan biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR43285	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCAP		Phenylalanine, tyrosine and tryptophan biosynthesis		ECO:0000037 not_recorded
PseudoCyc	TRPSYN-PWY	L-tryptophan biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae01110	Biosynthesis of secondary metabolites	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01230	Biosynthesis of amino acids	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01130	Biosynthesis of antibiotics	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00400	Phenylalanine, tyrosine and tryptophan biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	COMPLETE-ARO-PWY	superpathway of aromatic amino acid biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCyc	ALL-CHORISMATE-PWY	superpathway of chorismate metabolism	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Hamap	MF_00211	Anthranilate phosphoribosyltransferase [trpD].	IPR005940	Anthranilate phosphoribosyl transferase	5	339	37.749939
NCBIfam	TIGR01245	JCVI: anthranilate phosphoribosyltransferase	IPR005940	Anthranilate phosphoribosyl transferase	7	338	1.4E-120
FunFam	G3DSA:3.40.1030.10:FF:000002	Anthranilate phosphoribosyltransferase	-	-	73	342	1.9E-103
Gene3D	G3DSA:1.20.970.10	Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C	-	-	1	70	2.5E-29
Gene3D	G3DSA:3.40.1030.10	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	IPR035902	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily	73	347	1.8E-103
Coils	Coil	Coil	-	-	7	27	-
SUPERFAMILY	SSF52418	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	IPR035902	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily	75	340	1.57E-87
SUPERFAMILY	SSF47648	Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	IPR036320	Glycosyl transferase family 3, N-terminal domain superfamily	1	67	2.88E-21
Pfam	PF00591	Glycosyl transferase family, a/b domain	IPR000312	Glycosyl transferase, family 3	75	329	1.3E-101
Pfam	PF02885	Glycosyl transferase family, helical bundle domain	IPR017459	Glycosyl transferase family 3, N-terminal domain	6	65	2.2E-19
FunFam	G3DSA:1.20.970.10:FF:000006	Anthranilate phosphoribosyltransferase	-	-	1	70	8.2E-32
PANTHER	PTHR43285	ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE	IPR005940	Anthranilate phosphoribosyl transferase	2	341	3.1E-107

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.