Pseudomonas aeruginosa PAO1, PA0693 (exbB2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0693
Name
exbB2
Replicon chromosome
Genomic location 765315 - 767162 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_249384.1
GI 15595890
Affymetrix PA0693_exbB2_at
Entrez 880774
GenBank AAG04082.1
INSDC AAG04082.1
NCBI Locus Tag PA0693
protein_id(GenBank) gb|AAG04082.1|AE004505_3|gnl|PseudoCAP|PA0693
TIGR NTL03PA00694
UniParc UPI00000C5104
UniProtKB Acc Q9I5N3
UniProtKB ID Q9I5N3_PSEAE
UniRef100 UniRef100_Q9I5N3
UniRef50 UniRef50_Q4KCV6
UniRef90 UniRef90_Q9I5N3

Product

Feature Type CDS
Coding Frame 1
Product Name
transport protein ExbB2
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -5.33
Kyte-Doolittle Hydrophobicity Value 0.088
Molecular Weight (kDa) 65.2
Isoelectric Point (pI) 5.74

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 348 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000671 (366 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0693
Search term: exbB2

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Import of biopolymers into Escherichia coli: nucleotide sequences of the exbB and exbD genes are homologous to those of the tolQ and tolR genes, respectively.
Eick-Helmerich K, Braun V
J Bacteriol 1989 Sep;171(9):5117-26
PubMed ID: 2670903
Identification and characterization of the tolQRA genes of Pseudomonas aeruginosa.
Dennis JJ, Lafontaine ER, Sokol PA
J Bacteriol 1996 Dec;178(24):7059-68
PubMed ID: 8955385