Pseudomonas aeruginosa PAO1, PA0749

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0749
Name
Replicon chromosome
Genomic location 817082 - 817903 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249440.1
GI 15595946
Affymetrix PA0749_at
DNASU PaCD00006344
Entrez 879353
GenBank AAG04138.1
INSDC AAG04138.1
NCBI Locus Tag PA0749
protein_id(GenBank) gb|AAG04138.1|AE004510_2|gnl|PseudoCAP|PA0749
TIGR NTL03PA00750
UniParc UPI00000C5138
UniProtKB Acc Q9I5I0
UniProtKB ID Q9I5I0_PSEAE
UniRef100 UniRef100_Q9I5I0
UniRef50 UniRef50_A0A0B7DBN9
UniRef90 UniRef90_Q9I5I0

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Charge (pH 7) 19.21
Kyte-Doolittle Hydrophobicity Value -0.359
Molecular Weight (kDa) 31.9
Isoelectric Point (pI) 10.48

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
vanW gene in vanG cluster Also known as vanWG, is a vanW variant found in the vanG gene cluster. [PMID:16723588] ARO:3002965 protein homolog model Strict 142.1 31.58 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 105 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000723 (309 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0749

Human Homologs

References

Regulation of VanB-type vancomycin resistance gene expression by the VanS(B)-VanR (B) two-component regulatory system in Enterococcus faecalis V583.
Evers S, Courvalin P
J Bacteriol 1996 Mar;178(5):1302-9
PubMed ID: 8631706