Pseudomonas aeruginosa PAO1, PA0780 (pruR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006355 regulation of transcription, DNA-templated
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:2001158 positive regulation of proline catabolic process to glutamate
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 12270821 Reviewed by curator
Biological Process GO:0006562 proline catabolic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0006355 regulation of transcription, DNA-templated
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00342
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003700 DNA-binding transcription factor activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00342
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0043565 sequence-specific DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00342
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Proline utilization ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51182 RmlC-like cupins IPR011051 RmlC-like cupin domain superfamily 13 179 7.97E-7
Gene3D G3DSA:2.60.120.10 Jelly Rolls IPR014710 RmlC-like jelly roll fold 9 81 3.9E-6
PANTHER PTHR46796 HTH-TYPE TRANSCRIPTIONAL ACTIVATOR RHAS-RELATED - - 9 249 2.5E-49
SUPERFAMILY SSF46689 Homeodomain-like IPR009057 Homeobox-like domain superfamily 201 249 1.52E-10
SUPERFAMILY SSF46689 Homeodomain-like IPR009057 Homeobox-like domain superfamily 151 199 1.12E-9
SMART SM00342 aracneu4 IPR018060 DNA binding HTH domain, AraC-type 165 248 1.4E-30
FunFam G3DSA:1.10.10.60:FF:000492 AraC family transcriptional regulator - - 151 206 7.7E-38
Gene3D G3DSA:1.10.10.60 - - - 207 250 2.4E-12
Gene3D G3DSA:1.10.10.60 - - - 151 206 1.9E-15
Pfam PF12833 Helix-turn-helix domain IPR018060 DNA binding HTH domain, AraC-type 171 249 2.6E-21

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.