Pseudomonas aeruginosa PAO1, PA0795 (prpC)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0006099 | tricarboxylic acid cycle | Inferred from Direct Assay | ECO:0000314 direct assay evidence used in manual assertion |
7626013 | Reviewed by curator |
| Cellular Component | GO:0045239 | tricarboxylic acid cycle enzyme complex | Inferred from Direct Assay | ECO:0000314 direct assay evidence used in manual assertion |
7626013 | Reviewed by curator |
| Molecular Function | GO:0036440 | citrate synthase activity | Inferred from Direct Assay | ECO:0000314 direct assay evidence used in manual assertion |
7626013 | Reviewed by curator |
| Molecular Function | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer |
Inferred from Sequence Model
Term mapped from: InterPro:PR00143
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Cellular Component | GO:0005737 | cytoplasm |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01800
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0006099 | tricarboxylic acid cycle |
Inferred from Sequence Model
Term mapped from: InterPro:PR00143
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | pae00640 | Propanoate metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| PseudoCyc | TCA | TCA cycle I (prokaryotic) | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCyc | P22-PWY | acetyl-CoA assimilation | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCyc | P106-PWY | serine-isocitrate lyase pathway | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCAP | Citrate cycle (TCA cycle) |
ECO:0000037
not_recorded |
|||
| PseudoCyc | FERMENTATION-PWY | mixed acid fermentation | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCyc | GLYOXYLATE-BYPASS | glyoxylate cycle | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCyc | ANARESP1-PWY | anaerobic respiration | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCyc | TCA-GLYOX-BYPASS | superpathway of glyoxylate bypass and TCA | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCyc | GLYCOLYSIS-TCA-GLYOX-BYPASS | superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCAP | Glyoxylate and dicarboxylate metabolism |
ECO:0000037
not_recorded |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| PANTHER | PTHR11739 | CITRATE SYNTHASE | IPR002020 | Citrate synthase | 10 | 374 | 2.7E-99 |
| SUPERFAMILY | SSF48256 | Citrate synthase | IPR036969 | Citrate synthase superfamily | 10 | 375 | 3.01E-128 |
| PRINTS | PR00143 | Citrate synthase signature | IPR002020 | Citrate synthase | 251 | 271 | 7.5E-41 |
| PIRSF | PIRSF001369 | Citrate_synth | IPR024176 | Citrate synthase, bacterial-type | 3 | 375 | 1.4E-119 |
| FunFam | G3DSA:1.10.230.10:FF:000003 | Citrate synthase | - | - | 224 | 322 | 3.1E-40 |
| PRINTS | PR00143 | Citrate synthase signature | IPR002020 | Citrate synthase | 328 | 342 | 7.5E-41 |
| Gene3D | G3DSA:1.10.580.10 | Citrate Synthase, domain 1 | IPR016142 | Citrate synthase-like, large alpha subdomain | 22 | 347 | 0.0 |
| Gene3D | G3DSA:1.10.230.10 | - | IPR016143 | Citrate synthase-like, small alpha subdomain | 224 | 325 | 0.0 |
| PRINTS | PR00143 | Citrate synthase signature | IPR002020 | Citrate synthase | 308 | 324 | 7.5E-41 |
| PRINTS | PR00143 | Citrate synthase signature | IPR002020 | Citrate synthase | 176 | 191 | 7.5E-41 |
| PRINTS | PR00143 | Citrate synthase signature | IPR002020 | Citrate synthase | 126 | 139 | 7.5E-41 |
| Pfam | PF00285 | Citrate synthase, C-terminal domain | IPR002020 | Citrate synthase | 11 | 357 | 3.7E-120 |
| CDD | cd06108 | Ec2MCS_like | - | - | 10 | 372 | 0.0 |
| PRINTS | PR00143 | Citrate synthase signature | IPR002020 | Citrate synthase | 198 | 226 | 7.5E-41 |
| NCBIfam | TIGR01800 | JCVI: 2-methylcitrate synthase/citrate synthase II | IPR011278 | 2-methylcitrate synthase/citrate synthase type I | 11 | 375 | 0.0 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.