Pseudomonas aeruginosa PAO1, PA0809

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0809
Name
Replicon chromosome
Genomic location 886160 - 887476 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249500.1
GI 15596006
Affymetrix PA0809_at
Entrez 877623
GenBank AAG04198.1
INSDC AAG04198.1
NCBI Locus Tag PA0809
protein_id(GenBank) gb|AAG04198.1|AE004516_3|gnl|PseudoCAP|PA0809
TIGR NTL03PA00810
UniParc UPI000012F2A8
UniProtKB Acc Q9RPF2
UniProtKB ID MNTH2_PSEAE
UniRef100 UniRef100_Q9RPF2
UniRef50 UniRef50_Q9RPF2
UniRef90 UniRef90_Q9RPF2

Product

Feature Type CDS
Coding Frame 1
Product Name
probable transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 5.25
Kyte-Doolittle Hydrophobicity Value 0.825
Molecular Weight (kDa) 46.4
Isoelectric Point (pI) 8.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 298 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000782 (307 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0809

Human Homologs

Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 8.8e-61
Percent Identity: 38.2
Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 8.8e-61
Percent Identity: 38.2
Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 8.8e-61
Percent Identity: 38.2
Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 8.8e-61
Percent Identity: 38.2
Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 8.8e-61
Percent Identity: 38.2
Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 8.8e-61
Percent Identity: 38.2
Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 8.8e-61
Percent Identity: 38.2
Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 8.8e-61
Percent Identity: 38.2

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Genomic structure, promoter sequence, and induction of expression of the mouse Nramp1 gene in macrophages.
Govoni G, Vidal S, Cellier M, Lepage P, Malo D, Gros P
Genomics 1995 May 1;27(1):9-19
PubMed ID: 7665187
Nramp defines a family of membrane proteins.
Cellier M, Privé G, Belouchi A, Kwan T, Rodrigues V, Chia W, Gros P
Proc Natl Acad Sci U S A 1995 Oct 24;92(22):10089-93
PubMed ID: 7479731