Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA0867
|
Name |
mliC
|
Replicon | chromosome |
Genomic location | 948776 - 949159 (+ strand) |
Transposon Mutants | 5 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_249558.1 |
GI | 15596064 |
Affymetrix | PA0867_at |
DNASU | PaCD00006398 |
Entrez | 882238 |
GenBank | AAG04256.1 |
INSDC | AAG04256.1 |
NCBI Locus Tag | PA0867 |
protein_id(GenBank) | gb|AAG04256.1|AE004521_7|gnl|PseudoCAP|PA0867 |
TIGR | NTL03PA00868 |
UniParc | UPI00000C5199 |
UniProtKB Acc | Q9I574 |
UniProtKB ID | MLIC_PSEAE |
UniRef100 | UniRef100_Q9I574 |
UniRef50 | UniRef50_Q9I574 |
UniRef90 | UniRef90_Q9I574 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
membrane-bound lysozyme inhibitor of c-type lysozyme MliC
|
Synonyms | |
Evidence for Translation |
Detected using LC-MS/MS (13.70 kDa, PMID:21751344)
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -2.11 |
Kyte-Doolittle Hydrophobicity Value | -0.224 |
Molecular Weight (kDa) | 13.7 |
Isoelectric Point (pI) | 4.83 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
3F6Z | HYDROLASE | 11/07/08 | Crystal structure of Pseudomonas aeruginosa MliC in complex with hen egg white lysozyme | Gallus gallus; Pseudomonas aeruginosa | 2.5 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 33 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000834 (305 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA0867
Search term: mliC
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
A new family of lysozyme inhibitors contributing to lysozyme tolerance in gram-negative bacteria.
Callewaert L, Aertsen A, Deckers D, Vanoirbeek KG, Vanderkelen L, Van Herreweghe JM, Masschalck B, Nakimbugwe D, Robben J, Michiels CW
PLoS Pathog 2008 Mar 7;4(3):e1000019
PubMed ID: 18369469
|
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344
|