Pseudomonas aeruginosa PAO1, PA0932 (cysM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0004333 fumarate hydratase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006790 sulfur compound metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0004124 cysteine synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01136
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006535 cysteine biosynthetic process from serine
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01136
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Sulfur metabolism ECO:0000037
not_recorded
PseudoCAP Cysteine metabolism ECO:0000037
not_recorded
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc CYSTSYN-PWY L-cysteine biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Selenoamino acid metabolism ECO:0000037
not_recorded
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00920 Sulfur metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00270 Cysteine and methionine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR10314 CYSTATHIONINE BETA-SYNTHASE - - 9 297 2.2E-93
FunFam G3DSA:3.40.50.1100:FF:000003 Cystathionine beta-synthase - - 42 151 3.1E-43
FunFam G3DSA:3.40.50.1100:FF:000029 Cysteine synthase - - 152 293 4.9E-75
CDD cd01561 CBS_like - - 13 292 0.0
Coils Coil Coil - - 116 136 -
Pfam PF00291 Pyridoxal-phosphate dependent enzyme IPR001926 Tryptophan synthase beta chain-like, PALP domain 9 285 5.5E-68
NCBIfam TIGR01138 JCVI: cysteine synthase B IPR005858 Cysteine synthase CysM 7 296 0.0
Gene3D G3DSA:3.40.50.1100 - IPR036052 Tryptophan synthase beta chain-like, PALP domain superfamily 8 292 1.1E-111
SUPERFAMILY SSF53686 Tryptophan synthase beta subunit-like PLP-dependent enzymes IPR036052 Tryptophan synthase beta chain-like, PALP domain superfamily 5 294 2.23E-90
NCBIfam TIGR01136 JCVI: cysteine synthase IPR005856 Cysteine synthase 9 296 4.4E-124
Gene3D G3DSA:3.40.50.1100 - IPR036052 Tryptophan synthase beta chain-like, PALP domain superfamily 39 157 1.1E-111

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.