Pseudomonas aeruginosa PAO1, PA0934 (relA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0052381 tRNA dimethylallyltransferase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0015968 stringent response
IMP
Inferred from Mutant Phenotype 		ECO:0000315
mutant phenotype evidence used in manual assertion		 15385461 Reviewed by curator
Biological Process GO:0009405 pathogenesis
IMP
Inferred from Mutant Phenotype 		ECO:0000315
mutant phenotype evidence used in manual assertion		 15385461 Reviewed by curator
Biological Process GO:0050896 response to stimulus
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0015969 guanosine tetraphosphate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF04607
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Adaptation, Protection Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCyc PPGPPMET-PWY ppGpp biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.70.260 - - - 666 746 2.2E-18
PANTHER PTHR21262 GUANOSINE-3',5'-BIS DIPHOSPHATE 3'-PYROPHOSPHOHYDROLASE - - 18 743 0.0
FunFam G3DSA:3.10.20.30:FF:000002 GTP pyrophosphokinase (RelA/SpoT) - - 409 482 1.0E-31
FunFam G3DSA:3.30.70.260:FF:000075 GTP pyrophosphokinase - - 666 746 1.8E-52
SMART SM00954 RelA_SpoT_2 IPR007685 RelA/SpoT 262 372 3.9E-66
CDD cd04876 ACT_RelA-SpoT - - 672 743 1.88064E-21
NCBIfam TIGR00691 JCVI: RelA/SpoT family protein IPR004811 RelA/SpoT family 69 742 0.0
Pfam PF04607 Region found in RelA / SpoT proteins IPR007685 RelA/SpoT 262 370 8.4E-38
SUPERFAMILY SSF109604 HD-domain/PDEase-like - - 18 218 1.79E-49
SUPERFAMILY SSF81271 TGS-like IPR012676 TGS-like 407 475 5.01E-22
Gene3D G3DSA:1.10.3210.10 Hypothetical protein af1432 - - 11 218 9.3E-45
Pfam PF13328 HD domain - - 40 202 3.3E-45
CDD cd01668 TGS_RSH IPR033655 RelA/SpoT, TGS domain 417 475 6.22135E-34
Pfam PF13291 ACT domain IPR002912 ACT domain 666 743 1.0E-18
Pfam PF02824 TGS domain IPR004095 TGS 416 475 1.4E-21
SUPERFAMILY SSF81301 Nucleotidyltransferase IPR043519 Nucleotidyltransferase superfamily 207 420 2.62E-63
SUPERFAMILY SSF55021 ACT-like IPR045865 ACT-like domain 667 743 5.0E-15
Pfam PF19296 RelA/SpoT, AH and RIS domains IPR045600 RelA/SpoT, AH and RIS domains 493 638 1.9E-6
Gene3D G3DSA:3.10.20.30 - IPR012675 Beta-grasp domain superfamily 409 483 1.5E-31
CDD cd05399 NT_Rel-Spo_like IPR007685 RelA/SpoT 238 360 1.4441E-37
FunFam G3DSA:3.30.460.10:FF:000001 GTP pyrophosphokinase RelA - - 219 352 6.7E-59
FunFam G3DSA:1.10.3210.10:FF:000033 GTP pyrophosphokinase - - 11 218 0.0
Gene3D G3DSA:3.30.460.10 Beta Polymerase, domain 2 IPR043519 Nucleotidyltransferase superfamily 219 352 4.8E-49

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.