Pseudomonas aeruginosa PAO1, PA0985 (pyoS5)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0140911 pore-forming activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00280
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00280
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0050829 defense response to Gram-negative bacterium
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00280
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0031640 killing of cells of other organism
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00280
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Membrane proteins Other PAO1 genes in this class
Secreted Factors (toxins, enzymes, alginate) Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Coils Coil Coil - - 174 194 -
PRINTS PR00280 Channel forming colicin signature IPR000293 Channel forming colicin, C-terminal cytotoxic 374 390 1.1E-16
Coils Coil Coil - - 197 217 -
PRINTS PR00280 Channel forming colicin signature IPR000293 Channel forming colicin, C-terminal cytotoxic 432 445 1.1E-16
SUPERFAMILY SSF56837 Colicin - - 220 497 1.57E-81
Coils Coil Coil - - 282 320 -
PRINTS PR00280 Channel forming colicin signature IPR000293 Channel forming colicin, C-terminal cytotoxic 355 370 1.1E-16
Coils Coil Coil - - 241 261 -
Pfam PF01024 Colicin pore forming domain IPR000293 Channel forming colicin, C-terminal cytotoxic 310 494 9.9E-125
PRINTS PR00280 Channel forming colicin signature IPR000293 Channel forming colicin, C-terminal cytotoxic 446 464 1.1E-16
Gene3D G3DSA:1.10.490.30 Colicin IPR038283 Channel forming colicin, C-terminal domain superfamily 290 497 2.3E-70

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.