Pseudomonas aeruginosa PAO1, PA0994 (cupC3)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0994
Name
cupC3
Replicon chromosome
Genomic location 1074784 - 1077303 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_249685.1
GI 15596191
Affymetrix PA0994_at
Entrez 879339
GenBank AAG04383.1
INSDC AAG04383.1
NCBI Locus Tag PA0994
protein_id(GenBank) gb|AAG04383.1|AE004532_7|gnl|PseudoCAP|PA0994
TIGR NTL03PA00995
UniParc UPI00000C51F6
UniProtKB Acc Q9I4X5
UniProtKB ID Q9I4X5_PSEAE
UniRef100 UniRef100_Q9I4X5
UniRef50 UniRef50_Q9I4X5
UniRef90 UniRef90_Q9I4X5

Product

Feature Type CDS
Coding Frame 1
Product Name
usher CupC3
Product Name Confidence: Class 2
Synonyms probable fimbrial biogenesis usher protein
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.61
Kyte-Doolittle Hydrophobicity Value -0.362
Molecular Weight (kDa) 91.5
Isoelectric Point (pI) 7.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Outer Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 62 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000957 (823 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0994
Search term: cupC3
Search term: usher CupC3

Human Homologs

References

The fimD gene required for cell surface localization of Escherichia coli type 1 fimbriae.
Klemm P, Christiansen G
Mol Gen Genet 1990 Jan;220(2):334-8
PubMed ID: 1970114
Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes.
Burland V, Plunkett G 3rd, Sofia HJ, Daniels DL, Blattner FR
Nucleic Acids Res 1995 Jun 25;23(12):2105-19
PubMed ID: 7610040