Pseudomonas aeruginosa PAO1, PA1083 (flgH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1083
Name
flgH
Replicon chromosome
Genomic location 1169115 - 1169810 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249774.1
GI 15596280
Affymetrix PA1083_flgH_at
DNASU PaCD00006500
Entrez 879458
GenBank AAG04472.1
INSDC AAG04472.1
NCBI Locus Tag PA1083
protein_id(GenBank) gb|AAG04472.1|AE004539_14|gnl|PseudoCAP|PA1083
TIGR NTL03PA01084
UniParc UPI000012A921
UniProtKB Acc Q9I4P6
UniProtKB ID FLGH_PSEAE
UniRef100 UniRef100_B7UXA6
UniRef50 UniRef50_Q52081
UniRef90 UniRef90_A6V9B2

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellar L-ring protein precursor FlgH
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -0.04
Kyte-Doolittle Hydrophobicity Value -0.232
Molecular Weight (kDa) 24.5
Isoelectric Point (pI) 6.75

Subcellular localization

Individual Mappings
Localization Confidence PMID
Flagellar
Note: This is based on PSORTb V3.0 secondary localization prediction
 Class 3
Outer Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0273
Category Flagella
Evidence
Host Organism
Notes
Reference 14617143

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 234 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001045 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1083
Search term: flgH

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
L-, P-, and M-ring proteins of the flagellar basal body of Salmonella typhimurium: gene sequences and deduced protein sequences.
Jones CJ, Homma M, Macnab RM
J Bacteriol 1989 Jul;171(7):3890-900
PubMed ID: 2544561
Molecular cloning of two Pseudomonas flagellin genes and basal body structural genes.
Winstanley C, Morgan JA, Pickup RW, Saunders JR
Microbiology (Reading) 1994 Aug;140 ( Pt 8):2019-31
PubMed ID: 7921252