Pseudomonas aeruginosa PAO1, PA1095

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1095
Name
Synonym: fliS
Replicon chromosome
Genomic location 1186606 - 1186986 (+ strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249786.1
GI 15596292
Affymetrix PA1095_at
DNASU PaCD00006505
Entrez 881896
GenBank AAG04484.1
INSDC AAG04484.1
NCBI Locus Tag PA1095
protein_id(GenBank) gb|AAG04484.1|AE004540_4|gnl|PseudoCAP|PA1095
TIGR NTL03PA01096
UniParc UPI000012AA39
UniProtKB Acc Q9I4N6
UniProtKB ID FLISB_PSEAE
UniRef100 UniRef100_Q9I4N6
UniRef50 UniRef50_Q9I4N6
UniRef90 UniRef90_Q9I4N6

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.53
Kyte-Doolittle Hydrophobicity Value -0.189
Molecular Weight (kDa) 13.8
Isoelectric Point (pI) 4.74

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0273
Category Flagella
Evidence
Host Organism
Notes
Reference 14617143

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 216 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001056 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1095

Human Homologs

References

Vibrio parahaemolyticus FlaJ, a homologue of FliS, is required for production of a flagellin.
Stewart BJ, McCarter LL
Mol Microbiol 1996 Apr;20(1):137-49
PubMed ID: 8861212