Pseudomonas aeruginosa PAO1, PA1102 (fliG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1102
Name
fliG
Replicon chromosome
Genomic location 1194207 - 1195223 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249793.1
GI 15596299
Affymetrix PA1102_fliG_at
Entrez 882074
GenBank AAG04491.1
INSDC AAB06802.1
NCBI Locus Tag PA1102
protein_id(GenBank) gb|AAG04491.1|AE004540_11|gnl|PseudoCAP|PA1102
TIGR NTL03PA01103
UniParc UPI000012A9B0
UniProtKB Acc Q51464
UniProtKB ID FLIG_PSEAE
UniRef100 UniRef100_Q51464
UniRef50 UniRef50_Q9X4Q9
UniRef90 UniRef90_Q51464

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellar motor switch protein FliG
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -13.77
Kyte-Doolittle Hydrophobicity Value -0.136
Molecular Weight (kDa) 37.0
Isoelectric Point (pI) 4.66

Subcellular localization

Individual Mappings
Localization Confidence PMID
Flagellar
Note: This is based on PSORTb V3.0 secondary localization prediction
 Class 3
Cytoplasmic Membrane Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0273
Category Flagella
Evidence
Host Organism
Notes
Reference 14617143

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 313 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001063 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1102
Search term: fliG

Human Homologs

References

Gene sequence, overproduction, purification and determination of the wild-type level of the Escherichia coli flagellar switch protein FliG.
Roman SJ, Frantz BB, Matsumura P
Gene 1993 Oct 29;133(1):103-8
PubMed ID: 8224881
Cloning and characterization of Pseudomonas aeruginosa fliF, necessary for flagellar assembly and bacterial adherence to mucin.
Arora SK, Ritchings BW, Almira EC, Lory S, Ramphal R
Infect Immun 1996 Jun;64(6):2130-6
PubMed ID: 8675317