Pseudomonas aeruginosa PAO1, PA1108

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1108
Name
Replicon chromosome
Genomic location 1200063 - 1201220 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249799.1
GI 15596305
Affymetrix PA1108_at
Entrez 883036
GenBank AAG04497.1
INSDC AAG04497.1
NCBI Locus Tag PA1108
protein_id(GenBank) gb|AAG04497.1|AE004541_2|gnl|PseudoCAP|PA1108
TIGR NTL03PA01109
UniParc UPI00000C524F
UniProtKB Acc Q9I4M7
UniProtKB ID Q9I4M7_PSEAE
UniRef100 UniRef100_S0HZ25
UniRef50 UniRef50_S0HZ25
UniRef90 UniRef90_S0HZ25

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 7.61
Kyte-Doolittle Hydrophobicity Value 0.771
Molecular Weight (kDa) 40.6
Isoelectric Point (pI) 9.77

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 372 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001068 (312 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1108

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Characterization of the nonenzymatic chloramphenicol resistance (cmlA) gene of the In4 integron of Tn1696: similarity of the product to transmembrane transport proteins.
Bissonnette L, Champetier S, Buisson JP, Roy PH
J Bacteriol 1991 Jul;173(14):4493-502
PubMed ID: 1648560