Pseudomonas aeruginosa PAO1, PA1131

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1131
Name
Replicon chromosome
Genomic location 1223060 - 1224328 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249822.1
GI 15596328
Affymetrix PA1131_at
Entrez 878079
GenBank AAG04520.1
INSDC AAG04520.1
NCBI Locus Tag PA1131
protein_id(GenBank) gb|AAG04520.1|AE004543_4|gnl|PseudoCAP|PA1131
TIGR NTL03PA01132
UniParc UPI00000C5265
UniProtKB Acc Q9I4K4
UniProtKB ID Q9I4K4_PSEAE
UniRef100 UniRef100_S0IDR4
UniRef50 UniRef50_B7UX56
UniRef90 UniRef90_B7UX56

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 13.22
Kyte-Doolittle Hydrophobicity Value 0.864
Molecular Weight (kDa) 44.3
Isoelectric Point (pI) 10.49

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 473 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001091 (306 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1131

Human Homologs

Ensembl 110, assembly GRCh38.p14
major facilitator superfamily domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16894]
E-value: 1.8e-10
Percent Identity: 30.7
Ensembl 110, assembly GRCh38.p14
major facilitator superfamily domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16894]
E-value: 1.8e-10
Percent Identity: 30.7

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Nucleotide sequence analysis of the class G tetracycline resistance determinant from Vibrio anguillarum.
Zhao J, Aoki T
Microbiol Immunol 1992;36(10):1051-60
PubMed ID: 1479961