Pseudomonas aeruginosa PAO1, PA1158

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1158
Name
Replicon chromosome
Genomic location 1256094 - 1257452 (+ strand)
Transposon Mutants 6 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249849.1
GI 15596355
Affymetrix PA1158_at
Entrez 878647
GenBank AAG04547.1
INSDC AAG04547.1
NCBI Locus Tag PA1158
protein_id(GenBank) gb|AAG04547.1|AE004546_2|gnl|PseudoCAP|PA1158
TIGR NTL03PA01159
UniParc UPI00000C527C
UniProtKB Acc Q9I4H9
UniProtKB ID Q9I4H9_PSEAE
UniRef100 UniRef100_W0YNI8
UniRef50 UniRef50_Q4K871
UniRef90 UniRef90_A6V940

Product

Feature Type CDS
Coding Frame 1
Product Name
probable two-component sensor
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 0.55
Kyte-Doolittle Hydrophobicity Value -0.205
Molecular Weight (kDa) 51.0
Isoelectric Point (pI) 7.11

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 622 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001117 (505 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1158

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
In vivo characterization of tus gene expression in Escherichia coli.
Roecklein BA, Kuempel PL
Mol Microbiol 1992 Jun;6(12):1655-61
PubMed ID: 1495392