Pseudomonas aeruginosa PAO1, PA1162 (dapE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004530 deoxyribonuclease I activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006554 lysine catabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0016787 hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01546
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009089 lysine biosynthetic process via diaminopimelate
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01690
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0009014 succinyl-diaminopimelate desuccinylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01690
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00300 Lysine biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Lysine degradation ECO:0000037
not_recorded
KEGG pae01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc P4-PWY superpathway of L-lysine, L-threonine and L-methionine biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc DAPLYSINESYN-PWY L-lysine biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR43808 ACETYLORNITHINE DEACETYLASE - - 9 381 6.0E-67
FunFam G3DSA:3.40.630.10:FF:000010 Succinyl-diaminopimelate desuccinylase - - 263 383 9.9E-55
SUPERFAMILY SSF55031 Bacterial exopeptidase dimerisation domain IPR036264 Bacterial exopeptidase dimerisation domain 187 296 4.04E-30
Gene3D G3DSA:3.40.630.10 Zn peptidases - - 9 253 2.7E-57
Gene3D G3DSA:3.40.630.10 Zn peptidases - - 265 383 4.4E-19
SUPERFAMILY SSF53187 Zn-dependent exopeptidases - - 9 382 1.07E-64
Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria 9 383 51.891804
Pfam PF01546 Peptidase family M20/M25/M40 IPR002933 Peptidase M20 69 379 4.7E-41
Pfam PF07687 Peptidase dimerisation domain IPR011650 Peptidase M20, dimerisation domain 183 289 1.4E-27
FunFam G3DSA:3.30.70.360:FF:000011 Succinyl-diaminopimelate desuccinylase - - 187 297 4.2E-35
NCBIfam TIGR01246 JCVI: succinyl-diaminopimelate desuccinylase IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria 12 381 0.0
CDD cd03891 M20_DapE_proteobac - - 12 378 0.0
FunFam G3DSA:3.40.630.10:FF:000005 Succinyl-diaminopimelate desuccinylase - - 9 252 7.1E-129

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.