Pseudomonas aeruginosa PAO1, PA1174 (napA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006091 generation of precursor metabolites and energy
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0004450 isocitrate dehydrogenase (NADP+) activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00926
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030151 molybdenum ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01630
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008940 nitrate reductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01630
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0043546 molybdopterin cofactor binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01568
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Energy metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Nitrogen metabolism ECO:0000037
not_recorded
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00910 Nitrogen metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:2.40.40.20 - - - 702 825 3.8E-53
PANTHER PTHR43105 RESPIRATORY NITRATE REDUCTASE - - 37 825 0.0
Pfam PF00384 Molybdopterin oxidoreductase IPR006656 Molybdopterin oxidoreductase 93 566 1.8E-86
CDD cd02791 MopB_CT_Nitrate-R-NapA-like IPR041957 Nitrate reductase NapA-like, molybdopterin-binding domain 709 824 7.50087E-54
FunFam G3DSA:2.40.40.20:FF:000005 Periplasmic nitrate reductase - - 702 826 2.0E-52
Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain 38 89 1.4E-14
Gene3D G3DSA:3.40.50.740 - - - 93 621 0.0
Hamap MF_01630 Periplasmic nitrate reductase [napA]. IPR010051 Periplasmic nitrate reductase, large subunit 1 826 31.707886
Pfam PF01568 Molydopterin dinucleotide binding domain IPR006657 Molybdopterin dinucleotide-binding domain 712 820 1.2E-24
CDD cd02754 MopB_Nitrate-R-NapA-like - - 40 702 0.0
SUPERFAMILY SSF53706 Formate dehydrogenase/DMSO reductase, domains 1-3 - - 32 643 0.0
SUPERFAMILY SSF50692 ADC-like IPR009010 Aspartate decarboxylase-like domain superfamily 685 824 4.14E-42
NCBIfam TIGR01706 JCVI: periplasmic nitrate reductase subunit alpha IPR010051 Periplasmic nitrate reductase, large subunit 12 824 0.0
SMART SM00926 Molybdop_Fe4S4_2 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain 36 90 4.3E-9
Gene3D G3DSA:3.30.200.210 - - - 37 664 0.0
Gene3D G3DSA:3.40.228.10 Dimethylsulfoxide Reductase, domain 2 - - 172 701 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.