Pseudomonas aeruginosa PAO1, PA1175 (napD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1175
Name
napD
Replicon chromosome
Genomic location 1275795 - 1276124 (- strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_249866.1
GI 15596372
Affymetrix PA1175_napD_at
DNASU PaCD00006541
Entrez 879211
GenBank AAG04564.1
INSDC AAG04564.1
NCBI Locus Tag PA1175
protein_id(GenBank) gb|AAG04564.1|AE004547_10|gnl|PseudoCAP|PA1175
TIGR NTL03PA01176
UniParc UPI00000C528D
UniProtKB Acc Q9I4G2
UniProtKB ID Q9I4G2_PSEAE
UniRef100 UniRef100_W0YL75
UniRef50 UniRef50_W0YL75
UniRef90 UniRef90_W0YL75

Product

Feature Type CDS
Coding Frame 1
Product Name
NapD protein of periplasmic nitrate reductase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -13.10
Kyte-Doolittle Hydrophobicity Value -0.131
Molecular Weight (kDa) 12.0
Isoelectric Point (pI) 4.04

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 50 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001133 (345 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1175
Search term: napD

Human Homologs

References

The napEDABC gene cluster encoding the periplasmic nitrate reductase system of Thiosphaera pantotropha.
Berks BC, Richardson DJ, Reilly A, Willis AC, Ferguson SJ
Biochem J 1995 Aug 1;309 ( Pt 3)(Pt 3):983-92
PubMed ID: 7639719
A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map.
Itoh T, Aiba H, Baba T, Hayashi K, Inada T, Isono K, Kasai H, Kimura S, Kitakawa M, Kitagawa M, Makino K, Miki T, Mizobuchi K, Mori H, Mori T, Motomura K, Nakade S, Nakamura Y, Nashimoto H, Nishio Y, Oshima T, Saito N, Sampei G, Seki Y, Horiuchi T
DNA Res 1996 Dec 31;3(6):379-92
PubMed ID: 9097040
Periplasmic nitrate-reducing system of the phototrophic bacterium Rhodobacter sphaeroides DSM 158: transcriptional and mutational analysis of the napKEFDABC gene cluster.
Reyes F, Gavira M, Castillo F, Moreno-Vivián C
Biochem J 1998 May 1;331 ( Pt 3)(Pt 3):897-904
PubMed ID: 9560320