Pseudomonas aeruginosa PAO1, PA1185

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1185
Name
Synonym: yfcG
Replicon chromosome
Genomic location 1286990 - 1287619 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249876.1
GI 15596382
Affymetrix PA1185_at
DNASU PaCD00006546
Entrez 880645
GenBank AAG04574.1
INSDC AAG04574.1
NCBI Locus Tag PA1185
protein_id(GenBank) gb|AAG04574.1|AE004549_1|gnl|PseudoCAP|PA1185
TIGR NTL03PA01186
UniParc UPI00000C5295
UniProtKB Acc Q9I4F3
UniProtKB ID Q9I4F3_PSEAE
UniRef100 UniRef100_A0A080VZV3
UniRef50 UniRef50_D4XGW0
UniRef90 UniRef90_A6V905

Product

Feature Type CDS
Coding Frame 1
Product Name
probable glutathione S-transferase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -0.60
Kyte-Doolittle Hydrophobicity Value -0.279
Molecular Weight (kDa) 24.0
Isoelectric Point (pI) 6.87

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 228 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001143 (308 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1185

Human Homologs

References

The URE2 gene product of Saccharomyces cerevisiae plays an important role in the cellular response to the nitrogen source and has homology to glutathione s-transferases.
Coschigano PW, Magasanik B
Mol Cell Biol 1991 Feb;11(2):822-32
PubMed ID: 1990286