Pseudomonas aeruginosa PAO1, PA1243

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0007165	signal transduction	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00512	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0000155	phosphorelay sensor kinase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00512	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0016310	phosphorylation	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0000160	phosphorelay signal transduction system	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00072	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016772	transferase activity, transferring phosphorus-containing groups	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCAP		Two-component System		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	651	665	1.5E-14
SUPERFAMILY	SSF47384	Homodimeric domain of signal transducing histidine kinase	IPR036097	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily	490	558	4.32E-11
Pfam	PF08448	PAS fold	IPR013656	PAS fold-4	351	458	1.5E-11
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	682	700	1.5E-14
NCBIfam	TIGR00229	JCVI: PAS domain S-box protein	IPR000014	PAS domain	342	463	2.4E-14
Pfam	PF00072	Response regulator receiver domain	IPR001789	Signal transduction response regulator, receiver domain	744	850	7.8E-17
SMART	SM00387	HKATPase_4	IPR003594	Histidine kinase/HSP90-like ATPase	602	722	1.7E-24
SMART	SM00086	pac_2	IPR001610	PAC motif	126	169	26.0
SMART	SM00091	pas_2	IPR000014	PAS domain	345	411	7.3E-7
Pfam	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	IPR003594	Histidine kinase/HSP90-like ATPase	604	720	3.9E-16
SUPERFAMILY	SSF55785	PYP-like sensor domain (PAS domain)	IPR035965	PAS domain superfamily	75	175	5.76E-6
Pfam	PF08448	PAS fold	IPR013656	PAS fold-4	74	171	1.6E-7
Coils	Coil	Coil	-	-	456	487	-
Gene3D	G3DSA:3.30.450.20	PAS domain	-	-	53	176	4.7E-21
SUPERFAMILY	SSF55781	GAF domain-like	-	-	171	337	2.4E-15
Gene3D	G3DSA:1.10.287.130	-	-	-	488	560	1.3E-17
Gene3D	G3DSA:3.30.565.10	-	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	562	731	1.9E-40
Gene3D	G3DSA:3.40.50.2300	-	-	-	742	858	6.2E-26
CDD	cd00130	PAS	IPR000014	PAS domain	354	453	7.04961E-11
CDD	cd16919	HATPase_CckA-like	-	-	607	719	1.28434E-61
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	669	679	1.5E-14
SUPERFAMILY	SSF55874	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	552	722	2.23E-37
Pfam	PF00512	His Kinase A (phospho-acceptor) domain	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	497	559	7.4E-9
SUPERFAMILY	SSF55785	PYP-like sensor domain (PAS domain)	IPR035965	PAS domain superfamily	334	454	4.01E-22
SMART	SM00448	REC_2	IPR001789	Signal transduction response regulator, receiver domain	742	850	1.8E-22
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	706	719	1.5E-14
Gene3D	G3DSA:3.30.450.20	PAS domain	-	-	343	475	9.9E-24
SMART	SM00388	HisKA_10	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	496	561	4.8E-9
SMART	SM00086	pac_2	IPR001610	PAC motif	414	456	3.2E-7
CDD	cd18161	REC_hyHK_blue-like	-	-	744	841	2.55849E-36
PANTHER	PTHR43065	SENSOR HISTIDINE KINASE	-	-	337	727	5.6E-73
SUPERFAMILY	SSF52172	CheY-like	IPR011006	CheY-like superfamily	741	855	7.97E-28
CDD	cd00082	HisKA	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	494	557	1.59998E-9
Gene3D	G3DSA:3.30.450.40	-	IPR029016	GAF-like domain superfamily	177	342	6.5E-9

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.