Pseudomonas aeruginosa PAO1, PA1253 (lhpG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0047533 2,5-dioxovalerate dehydrogenase (NADP+) activity
IDA
Inferred from Direct Assay 		ECO:0000005
enzyme assay evidence		 22833679 Reviewed by curator
Biological Process GO:0019470 4-hydroxyproline catabolic process
IDA
Inferred from Direct Assay 		ECO:0000005
enzyme assay evidence		 22833679 Reviewed by curator
Molecular Function GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.309.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.605.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Putative enzymes Other PAO1 genes in this class
Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00040 Pentose and glucuronate interconversions 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00053 Ascorbate and aldarate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.605.10 Aldehyde Dehydrogenase; Chain A, domain 1 IPR016162 Aldehyde dehydrogenase, N-terminal 6 264 2.9E-46
CDD cd07129 ALDH_KGSADH IPR044151 Alpha-ketoglutaric semialdehyde dehydrogenase 59 494 0.0
PANTHER PTHR43353 SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL - - 8 491 3.2E-63
FunFam G3DSA:3.40.605.10:FF:000037 NADP-dependent fatty aldehyde dehydrogenase - - 19 269 8.8E-103
Gene3D G3DSA:3.40.309.10 Aldehyde Dehydrogenase; Chain A, domain 2 IPR016163 Aldehyde dehydrogenase, C-terminal 265 456 2.2E-49
FunFam G3DSA:3.40.309.10:FF:000040 Probable aldehyde dehydrogenase - - 266 456 3.9E-77
Pfam PF00171 Aldehyde dehydrogenase family IPR015590 Aldehyde dehydrogenase domain 38 454 1.2E-46
SUPERFAMILY SSF53720 ALDH-like IPR016161 Aldehyde/histidinol dehydrogenase 22 516 8.12E-99

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.