Pseudomonas aeruginosa PAO1, PA1261 (lhpR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0045764 positive regulation of cellular amino acid metabolic process
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
27145750 Reviewed by curator
Biological Process GO:0051957 positive regulation of amino acid transport
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
27145750 Reviewed by curator
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF12833
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003700 DNA-binding transcription factor activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF12833
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0043565 sequence-specific DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF12833
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class
Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF46689 Homeodomain-like IPR009057 Homeobox-like domain superfamily 173 219 9.41E-14
Pfam PF08448 PAS fold IPR013656 PAS fold-4 4 106 3.7E-19
SMART SM00342 aracneu4 IPR018060 DNA binding HTH domain, AraC-type 133 215 8.0E-26
Pfam PF12833 Helix-turn-helix domain IPR018060 DNA binding HTH domain, AraC-type 140 216 2.3E-23
Coils Coil Coil - - 224 224 -
Gene3D G3DSA:3.30.450.20 PAS domain - - 1 112 8.1E-16
PANTHER PTHR46796 HTH-TYPE TRANSCRIPTIONAL ACTIVATOR RHAS-RELATED - - 25 217 2.5E-28
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 4 101 1.19E-11
Gene3D G3DSA:1.10.10.60 - - - 118 223 3.0E-30
PRINTS PR00032 AraC bacterial regulatory protein HTH signature IPR020449 Transcription regulator HTH, AraC- type 184 199 1.3E-7
PRINTS PR00032 AraC bacterial regulatory protein HTH signature IPR020449 Transcription regulator HTH, AraC- type 199 215 1.3E-7
SUPERFAMILY SSF46689 Homeodomain-like IPR009057 Homeobox-like domain superfamily 117 166 6.54E-7
CDD cd00130 PAS IPR000014 PAS domain 6 106 1.20206E-4

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.