Pseudomonas aeruginosa PAO1, PA1276 (cobC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009236 cobalamin biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
ECO:0000250
sequence similarity evidence used in manual assertion
2211520 Reviewed by curator
Molecular Function GO:0030170 pyridoxal phosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00155
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009058 biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00155
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009236 cobalamin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01140
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01140
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00860 Porphyrin and chlorophyll metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc aminopropanol phosphate biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
PseudoCAP Cobalamin biosynthesis ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF53383 PLP-dependent transferases IPR015424 Pyridoxal phosphate-dependent transferase 12 313 7.82E-56
PANTHER PTHR42885 HISTIDINOL-PHOSPHATE AMINOTRANSFERASE-RELATED - - 51 301 5.9E-32
Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase, domain 1 IPR015422 Pyridoxal phosphate-dependent transferase, small domain 23 300 2.8E-50
NCBIfam TIGR01140 JCVI: threonine-phosphate decarboxylase CobD IPR005860 L-threonine-O-3-phosphate decarboxylase 4 322 1.5E-109
Gene3D G3DSA:3.40.640.10 - IPR015421 Pyridoxal phosphate-dependent transferase, major domain 34 237 2.8E-50
Coils Coil Coil - - 231 261 -
CDD cd00609 AAT_like - - 23 231 1.22107E-30
Pfam PF00155 Aminotransferase class I and II IPR004839 Aminotransferase, class I/classII 54 308 1.2E-30

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.