Pseudomonas aeruginosa PAO1, PA1279 (cobU)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0051188 cofactor biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Biological Process GO:0009236 cobalamin biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Molecular Function GO:0004129 cytochrome-c oxidase activity
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Biological Process GO:0009236 cobalamin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF52733
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008939 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF52733
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009163 nucleoside biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR03160
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00860 Porphyrin and chlorophyll metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc 5-methoxy-6-methylbenzimidazolyl adenosylcobamide biosynthesis from adenosylcobinamide-GDP InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
PseudoCyc PWY-5509 adenosylcobalamin biosynthesis from cobyrinate a,c-diamide I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
PseudoCyc P381-PWY adenosylcobalamin biosynthesis II (late cobalt incorporation) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
MetaCyc adenosylcobalamin biosynthesis from adenosylcobinamide-GDP I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc 5-methoxybenzimidazolyl adenosylcobamide biosynthesis from adenosylcobinamide-GDP InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc 5-methylbenzimidazolyl adenosylcobamide biosynthesis from adenosylcobinamide-GDP InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-5508 adenosylcobalamin biosynthesis from cobyrinate a,c-diamide II 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
PseudoCyc COBALSYN-PWY adenosylcobalamin salvage from cobinamide I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
PseudoCAP Cobalamin biosynthesis ECO:0000037
not_recorded
MetaCyc 2-methyladeninyl adenosylcobamide biosynthesis from adenosylcobinamide-GDP InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc adeninyl adenosylcobamide biosynthesis from adenosylcobinamide-GDP InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc 5-hydroxybenzimidazolyl adenosylcobamide biosynthesis from adenosylcobinamide-GDP InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc superpathway of adenosylcobalamin salvage from cobinamide II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc benzimidazolyl adenosylcobamide biosynthesis from adenosylcobinamide-GDP InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae00860 Porphyrin and chlorophyll metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF02277 Phosphoribosyltransferase IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like 12 346 4.2E-130
Gene3D G3DSA:1.10.1610.10 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal 24 346 9.1E-128
SUPERFAMILY SSF52733 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily 4 347 2.75E-119
CDD cd02439 DMB-PRT_CobT IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like 29 344 2.10571E-125
TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic 14 346 0.0
Gene3D G3DSA:3.40.50.10210 56 329 9.1E-128
Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic 12 348 37.108

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.