Pseudomonas aeruginosa PAO1, PA1302 (hxuA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0038023 signaling receptor activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 18086184 Reviewed by curator
Molecular Function GO:0015232 heme transmembrane transporter activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:E7A868
 ECO:0000250
sequence similarity evidence used in manual assertion		 18086184 Reviewed by curator
Biological Process GO:0007166 cell surface receptor signaling pathway
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:E7A868
 ECO:0000250
sequence similarity evidence used in manual assertion		 18086184 Reviewed by curator
Biological Process GO:0015886 heme transport
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:E7A868
 ECO:0000250
sequence similarity evidence used in manual assertion		 18086184 Reviewed by curator
Molecular Function GO:0022857 transmembrane transporter activity

Cellular Component GO:0019867 outer membrane
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:E7A868
 ECO:0000250
sequence similarity evidence used in manual assertion		 18086184 Reviewed by curator
Biological Process GO:0015886 heme transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01785
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0022857 transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01786
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0019867 outer membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07660
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055085 transmembrane transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01786
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0015232 heme transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01785
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transport of small molecules Other PAO1 genes in this class
Membrane proteins Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.55.50.30:FF:000002 Probable TonB-dependent receptor - - 26 129 1.1E-36
Gene3D G3DSA:3.55.50.30 - - - 26 128 4.1E-25
FunFam G3DSA:2.40.170.20:FF:000014 TonB-dependent haem/haemoglobin receptor - - 247 850 0.0
CDD cd01347 ligand_gated_channel - - 137 848 3.5159E-59
Pfam PF00593 TonB dependent receptor IPR000531 TonB-dependent receptor-like, beta-barrel 339 848 2.1E-42
NCBIfam TIGR01786 JCVI: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor 127 848 3.7E-107
Pfam PF07715 TonB-dependent Receptor Plug Domain IPR012910 TonB-dependent receptor, plug domain 134 235 1.5E-18
SMART SM00965 STN_2 IPR011662 Secretin/TonB, short N-terminal domain 55 105 1.0E-11
PANTHER PTHR30442 IRON III DICITRATE TRANSPORT PROTEIN FECA IPR039426 TonB-dependent receptor-like 46 851 0.0
Pfam PF07660 Secretin and TonB N terminus short domain IPR011662 Secretin/TonB, short N-terminal domain 55 104 9.0E-8
Gene3D G3DSA:2.40.170.20 - IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily 246 850 4.3E-89
Gene3D G3DSA:2.170.130.10 - IPR037066 TonB-dependent receptor, plug domain superfamily 129 245 3.3E-29
NCBIfam TIGR01785 JCVI: TonB-dependent heme/hemoglobin receptor family protein IPR011276 TonB-dependent haem/haemoglobin receptor 130 849 1.9E-128
SUPERFAMILY SSF56935 Porins - - 109 849 3.66E-90
FunFam G3DSA:2.170.130.10:FF:000034 TonB-dependent receptor - - 129 245 7.4E-79

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.