Pseudomonas aeruginosa PAO1, PA1310 (phnW)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0047304	2-aminoethylphosphonate-pyruvate transaminase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	6406228	Reviewed by curator
Molecular Function	GO:0030170	pyridoxal phosphate binding	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	6406228	Reviewed by curator
Molecular Function	GO:0047304	2-aminoethylphosphonate-pyruvate transaminase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR03301	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0019700	organic phosphonate catabolic process	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR03301	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCyc	PHOSPHONOTASE-PWY	2-aminoethylphosphonate degradation I	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01120	Microbial metabolism in diverse environments	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
MetaCyc		2-aminoethylphosphonate degradation II	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG	pae00440	Phosphonate and phosphinate metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PIRSF	PIRSF000524	SPT	IPR024169	Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase	1	370	4.4E-62
Gene3D	G3DSA:3.40.640.10	-	IPR015421	Pyridoxal phosphate-dependent transferase, major domain	19	262	4.1E-110
Gene3D	G3DSA:3.90.1150.10	Aspartate Aminotransferase, domain 1	IPR015422	Pyridoxal phosphate-dependent transferase, small domain	11	354	4.1E-110
PANTHER	PTHR42778	2-AMINOETHYLPHOSPHONATE--PYRUVATE TRANSAMINASE	-	-	1	369	0.0
NCBIfam	TIGR02326	JCVI: 2-aminoethylphosphonate--pyruvate transaminase	IPR012703	2-aminoethylphosphonate--pyruvate transaminase	5	364	0.0
SUPERFAMILY	SSF53383	PLP-dependent transferases	IPR015424	Pyridoxal phosphate-dependent transferase	8	367	3.54E-84
Pfam	PF00266	Aminotransferase class-V	IPR000192	Aminotransferase class V domain	52	304	3.3E-15
Hamap	MF_01376	2-aminoethylphosphonate--pyruvate transaminase [phnW].	IPR012703	2-aminoethylphosphonate--pyruvate transaminase	1	371	208.059052
NCBIfam	TIGR03301	JCVI: 2-aminoethylphosphonate aminotransferase	IPR012703	2-aminoethylphosphonate--pyruvate transaminase	9	362	0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.