Pseudomonas aeruginosa PAO1, PA1335 (aauR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PP_1066
ECO:0000044
sequence similarity evidence
18310026 Reviewed by curator
Molecular Function GO:0043565 sequence-specific DNA binding
ISO
Inferred from Sequence Orthology
Term mapped from: PseudoCAP:PP_1066
ECO:0000201
sequence orthology evidence
18310026 Reviewed by curator
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00382
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0043565 sequence-specific DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01590
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00072
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008134 transcription factor binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class
Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Two-component System ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.40.50.2300:FF:000018 DNA-binding transcriptional regulator NtrC - - 3 118 1.4E-36
FunFam G3DSA:3.40.50.300:FF:000006 DNA-binding transcriptional regulator NtrC - - 123 300 1.3E-71
Gene3D G3DSA:1.10.8.60 - - - 301 372 2.8E-21
SMART SM00382 AAA_5 IPR003593 AAA+ ATPase domain 150 312 6.1E-8
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 5 175 5.27E-37
PANTHER PTHR32071 TRANSCRIPTIONAL REGULATORY PROTEIN - - 5 425 5.9E-129
Gene3D G3DSA:1.10.10.60 - - - 376 425 6.0E-13
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 130 359 4.32E-67
Pfam PF00158 Sigma-54 interaction domain IPR002078 RNA polymerase sigma factor 54 interaction domain 130 296 4.4E-66
CDD cd17549 REC_DctD-like - - 4 120 1.03068E-62
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 4 99 9.8E-22
CDD cd00009 AAA - - 131 294 3.1974E-25
Gene3D G3DSA:3.40.50.2300 - - - 2 129 6.3E-29
SUPERFAMILY SSF46689 Homeodomain-like IPR009057 Homeobox-like domain superfamily 342 424 5.38E-10
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 1 100 1.7E-16
PRINTS PR01590 FIS bacterial regulatory protein HTH signature IPR002197 DNA binding HTH domain, Fis-type 405 425 4.1E-7
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 130 300 2.7E-61
Pfam PF02954 Bacterial regulatory protein, Fis family IPR002197 DNA binding HTH domain, Fis-type 382 422 2.4E-8
PRINTS PR01590 FIS bacterial regulatory protein HTH signature IPR002197 DNA binding HTH domain, Fis-type 388 405 4.1E-7

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.