Pseudomonas aeruginosa PAO1, PA1344

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1344
Name
Synonym: yvaG
Replicon chromosome
Genomic location 1457729 - 1458523 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_250035.1
GI 15596541
Affymetrix PA1344_at
DNASU PaCD00006622
Entrez 880999
GenBank AAG04733.1
INSDC AAG04733.1
NCBI Locus Tag PA1344
protein_id(GenBank) gb|AAG04733.1|AE004564_2|gnl|PseudoCAP|PA1344
TIGR NTL03PA01345
UniParc UPI00000C5327
UniProtKB Acc Q9I400
UniProtKB ID Q9I400_PSEAE
UniRef100 UniRef100_W0YP46
UniRef50 UniRef50_R4Y1Z9
UniRef90 UniRef90_W0WHM3

Product

Feature Type CDS
Coding Frame 1
Product Name
probable short-chain dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.58
Kyte-Doolittle Hydrophobicity Value 0.216
Molecular Weight (kDa) 27.4
Isoelectric Point (pI) 4.94

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Unknown (This protein may have multiple localization sites) Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 651 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001279 (401 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1344

Human Homologs

Ensembl 110, assembly GRCh38.p14
dehydrogenase/reductase 4 [Source:HGNC Symbol;Acc:HGNC:16985]
E-value: 2.3e-24
Percent Identity: 35.5
Ensembl 110, assembly GRCh38.p14
dehydrogenase/reductase 4 [Source:HGNC Symbol;Acc:HGNC:16985]
E-value: 2.3e-24
Percent Identity: 35.5

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295