Pseudomonas aeruginosa PAO1, PA1417

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1417
Name
Replicon chromosome
Genomic location 1541145 - 1542746 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250108.1
GI 15596614
Affymetrix PA1417_at
Entrez 881729
GenBank AAG04806.1
INSDC AAG04806.1
NCBI Locus Tag PA1417
protein_id(GenBank) gb|AAG04806.1|AE004571_5|gnl|PseudoCAP|PA1417
TIGR NTL03PA01418
UniParc UPI00000C536E
UniProtKB Acc Q9I3S7
UniProtKB ID Q9I3S7_PSEAE
UniRef100 UniRef100_Q9I3S7
UniRef50 UniRef50_Q92S59
UniRef90 UniRef90_A0A072ZLI9

Product

Feature Type CDS
Coding Frame 1
Product Name
probable decarboxylase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.55
Kyte-Doolittle Hydrophobicity Value 0.042
Molecular Weight (kDa) 57.3
Isoelectric Point (pI) 6.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 594 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001338 (460 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1417

Human Homologs

Ensembl 110, assembly GRCh38.p14
2-hydroxyacyl-CoA lyase 1 [Source:HGNC Symbol;Acc:HGNC:17856]
E-value: 5.6e-33
Percent Identity: 24.8

References

The nucleotide sequence of the ilvBN operon of Escherichia coli: sequence homologies of the acetohydroxy acid synthase isozymes.
Wek RC, Hauser CA, Hatfield GW
Nucleic Acids Res 1985 Jun 11;13(11):3995-4010
PubMed ID: 2989782