Pseudomonas aeruginosa PAO1, PA1418

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1418
Name
Replicon chromosome
Genomic location 1542822 - 1544213 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq NP_250109.1
GI 15596615
Affymetrix PA1418_at
Entrez 881711
GenBank AAG04807.1
INSDC AAG04807.1
NCBI Locus Tag PA1418
protein_id(GenBank) gb|AAG04807.1|AE004571_6|gnl|PseudoCAP|PA1418
TIGR NTL03PA01419
UniParc UPI00000C536F
UniProtKB Acc Q9I3S6
UniProtKB ID Q9I3S6_PSEAE
UniRef100 UniRef100_S0ICW7
UniRef50 UniRef50_Q4KJW2
UniRef90 UniRef90_A6V890

Product

Feature Type CDS
Coding Frame 1
Product Name
probable sodium:solute symport protein
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 7.88
Kyte-Doolittle Hydrophobicity Value 0.912
Molecular Weight (kDa) 49.0
Isoelectric Point (pI) 9.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 459 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000284 (771 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1418

Human Homologs

Ensembl 110, assembly GRCh38.p14
solute carrier family 5 member 9 [Source:HGNC Symbol;Acc:HGNC:22146]
E-value: 2.7e-07
Percent Identity: 25.5

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Cotranscription of two genes necessary for ribosomal protein L11 methylation (prmA) and pantothenate transport (panF) in Escherichia coli K-12.
Vanet A, Plumbridge JA, Alix JH
J Bacteriol 1993 Nov;175(22):7178-88
PubMed ID: 8226664
Osmoregulation of the opuE proline transport gene from Bacillus subtilis: contributions of the sigma A- and sigma B-dependent stress-responsive promoters.
Spiegelhalter F, Bremer E
Mol Microbiol 1998 Jul;29(1):285-96
PubMed ID: 9701821