Pseudomonas aeruginosa PAO1, PA1479 (ccmE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1479
Name
ccmE
Synonym: cycJ
Synonym: pfcyt3
Replicon chromosome
Genomic location 1604599 - 1605087 (+ strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250170.1
GI 15596676
Affymetrix PA1479_ccmE_at
Entrez 881024
GenBank AAG04868.1
INSDC AAG04868.1
NCBI Locus Tag PA1479
protein_id(GenBank) gb|AAG04868.1|AE004577_3|gnl|PseudoCAP|PA1479
TIGR NTL03PA01480
UniParc UPI00000C539A
UniProtKB Acc Q9I3N3
UniProtKB ID CCME_PSEAE
UniRef100 UniRef100_Q9I3N3
UniRef50 UniRef50_Q9I3N3
UniRef90 UniRef90_Q9I3N3

Product

Feature Type CDS
Coding Frame 1
Product Name
cytochrome C-type biogenesis protein CcmE
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.29
Kyte-Doolittle Hydrophobicity Value -0.148
Molecular Weight (kDa) 17.2
Isoelectric Point (pI) 6.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 190 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001394 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1479
Search term: ccmE

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295