Pseudomonas aeruginosa PAO1, PA4450 (murA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008760 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 7608103 Reviewed by curator
Biological Process GO:0009252 peptidoglycan biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 7608103 Reviewed by curator
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF55205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.65.10.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019277 UDP-N-acetylgalactosamine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01555
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008760 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01555
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCyc KDO-PEP-LIPASYN-PWY KDO<SUB>2</SUB>-lipid A and peptidoglycan biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00550 Peptidoglycan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-6387 UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-DAP-containing) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc PEPTIDOGLYCANSYN-PWY peptidoglycan biosynthesis I (meso-diaminopimelate containing) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc PEP-LIPA-SYN-PWY peptidoglycan and lipid A precursor biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00520 Amino sugar and nucleotide sugar metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd01555 UdpNAET IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase 12 412 0.0
Gene3D G3DSA:3.65.10.10 Enolpyruvate transferase domain IPR036968 Enolpyruvate transferase domain superfamily 4 416 0.0
NCBIfam TIGR01072 JCVI: UDP-N-acetylglucosamine 1-carboxyvinyltransferase IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 418 0.0
SUPERFAMILY SSF55205 EPT/RTPC-like IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta 1 419 0.0
Gene3D G3DSA:3.65.10.10 Enolpyruvate transferase domain IPR036968 Enolpyruvate transferase domain superfamily 21 231 0.0
Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) IPR001986 Enolpyruvate transferase domain 7 409 5.3E-120
FunFam G3DSA:3.65.10.10:FF:000002 UDP-N-acetylglucosamine 1-carboxyvinyltransferase - - 217 417 2.6E-102
PANTHER PTHR43783 UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE - - 2 420 0.0
Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 419 45.312771

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.